Table 2. Clinicopathological characteristics of CY+ and CY- patients with resectable pancreatic cancer.

Outcome	Ref. included	No. of patients (CY+ vs CY-)	Heterogeneity test			Model used	OR	95%CI	P value
			Chi-square	P value	I-square
Age (older vs younger)	[11, 13, 15]	74 vs 514	7.83	0.020	74.5%	Random model	2.40	0.38–15.38	0.354
Sex (male vs female)	[11–16, 18]	211 vs 1926	10.14	0.119	40.8%	Fixed model	0.96	0.71–1.29	0.762
Tumor size (larger vs smaller)	[11, 13, 15, 16]	94 vs 748	9.79	0.020	69.4%	Random model	11.65	2.62–51.86	0.001
Tumor location (head vs body/tail)	[11–15, 18]	177 vs 1673	6.60	0.169	39.4%	Fixed model	0.37	0.27–0.52	0.000
Tumor grade (poor vs well/moderate)	[11, 13, 14, 16]	64 vs 531	1.71	0.635	0%	Fixed model	0.89	0.40–1.97	0.776
Retroperitoneal invasion (Yes or No)	[11, 15, 16, 20]	92 vs 721	2.64	0.450	0%	Fixed model	1.63	0.97–2.72	0.063
Serosal invasion(yes or no)	[11, 15, 16, 20]	92 vs 721	4.27	0.234	29.7%	Fixed model	3.89	2.26–6.71	0.000
Portal vein invasion(yes or no)	[11, 15, 16]	76 vs 606	2.45	0.294	18.2%	Fixed model	1.82	1.12–2.95	0.016
Arterial invasion(yes or no)	[11, 15, 16]	76 vs 606	1.83	0.401	0%	Fixed model	1.85	0.86–3.96	0.115
Lymph vessel invasion(yes or no)	[11, 13, 14]	44 vs 297	0.34	0.842	0%	Fixed model	2.71	1.13–6.50	0.026
Perineural invasion(yes or no)	[11, 13, 15, 16]	94 vs 748	1.11	0.776	0%	Fixed model	0.93	0.53–1.61	0.785
Venous invasion(yes or no)	[11, 13, 14]	44 vs 297	2.51	0.285	20.3%	Fixed model	2.80	1.06–7.41	0.285
T stage(T3+4 vs T1+2)	[11–14, 19]	118 vs 1268	0.62	0.961	0%	Fixed model	2.65	1.06–6.63	0.037
N stage(N1 vs N0)	[11–14, 19]	118 vs 1268	6.33	0.176	36.8%	Fixed model	2.34	1.44–3.82	0.001