Table 1. Patient's characteristics.
| Characteristics | N | XAF1-M % (N) | IDH1mut % (N) |
|---|---|---|---|
| All patients | 80 | 32.5 (26) | 25.0 (20) |
| Women | 24 | 29.2 (7) | 25.0 (6) |
| Men | 56 | 33.9 (19) | 25.0 (14) |
| Age < 70 | 56 | 41.1 (23) | 35.7 (20) |
| Age ≥ 70 | 24 | 12.5 (3) | 0.0 (0) |
| Grade III* | 26 | 69.2 (18) | 69.2 (18) |
| Grade IV* | 54 | 14.8 (8) | 3.7 (2) |
| AA, AOA, AO IDH1mut | 18 | 100.0 (18) | 100.0 (18) |
| AA, AOA, AO IDH1wt | 8 | 0.0 (0) | 0.0 (0) |
| GB IDH1mut | 2 | 100.0 (2) | 100.0 (2) |
| GB IDH1wt | 54 | 11.1 (6) | 0.0 (0) |
XAF1 promoter methylation (XAF1-M) was determined by MS-HRM and IDH1 mutation.
(IDH1mut) by pyrosequencing and IHC. *Histological tumor grade: AA: anaplastic astrocytoma;
AO: anaplastic oligodendroglioma; AOA: anaplastic oligoastrocytoma; GB: glioblastoma.