Skip to main content
. 2017 Jan 4;8(9):15441–15452. doi: 10.18632/oncotarget.14487

Figure 5. L1 is related with in vivo chemoresistance of retinoblastoma and diffusely expressed in chemoresistant human retinoblastoma tumors.

Figure 5

A. The proportion of tumors with grade 0, 1, 2, and 3 on the visual grading system for the orthotopic transplantation model of retinoblastoma in mice. B. The proportion of tumors with Flexner-Wintersteiner rosettes in naïve and chemoresistant tumors. C. A representative photograph of L1-positive areas in chemoresistant tumors. Control, SNUOT-Rb1 cells; F-W, Flexner-Wintersteiner; L1 OE, SNUOT-Rb1 cells transfected with a lentiviral vector containing full length L1. Scale bar, 25 μm.