Figure 5. Effect of miR-27a on the SFRP1 mRNA and protein expressions among the six groups.
A. comparison of SFRP1 mRNA expression among six groups; B. comparison of SFRP1 protein expression among the six groups; C. SFRP1 protein expression among six groups detected by Western blot.
Note: miR-27a, microRNA-27a; SFRP1, secreted frizzled-related protein 1; *, compared with the control group, P < 0.05 (the miR-27a mimics group vs. the control group, P = 0.029 for SFRP1 mRNA, P = 0.036 for SFRP1 protein; the miR-27a inhibitors group vs. the control group, P = 0.044 for SFRP1 mRNA, P = 0.031 for SFRP1 protein; the si-SFRP1 group vs. the control group, P = 0.021 for SFRP1 mRNA, P = 0.022 for SFRP1 protein); #, compared with the si-SFRP1 group, P < 0.05 (the miR-27a inhibitors + si-SFRP1 group vs. the si-SFRP1 group, P = 0.023 for SFRP1 mRNA, P < 0.001 for SFRP1 protein).