Table 3. Univariate analysis for disease-free survival and overall survival.
| Variables | P value | DFSHR (95 % CI) | P value | OSHR (95 % CI) |
|---|---|---|---|---|
| Age (≤60vs >60) | 0.885 | 1.017(0.812–1.274) | 0.824 | 1.026(0.819 –1.285) |
| Sex (male vs female) | 0.647 | 0.945(0.742 – 1.203) | 0.366 | 0.895(0.703 – 1.139) |
| Lesion (peripheral vs central) | 0.028 | 1.313(1.030 –1.674) | 0.020 | 1.336(1.048 – 1.703) |
| Pathological stage (I, II, IIIA) | <0.001 | 1.848(1.618– 2.111) | <0.001 | 1.846(1.616 – 2.110) |
| Smoking (yes vs no) | 0.822 | 0.973(0.766 – 1.236) | 0.387 | 0.900(0.708– 1.143) |
| Tumor location (left vs right) | 0.630 | 0.945(0.752 –1.188) | 0.619 | 0.944(0.751– 1.186) |
| Histological subtype (adenocarcinoma, SqCC, others) | 1.000 | 1.000(0.849 –1.178) | 0.965 | 0.996(0.845– 1.174) |
| Resection type (pneumonectomy, lobectomy) | 0.032 | 1.414(1.030 – 1.940) | 0.044 | 1.385(1.009 – 1.902) |
| RDW (≥13.0 vs <13.0 %) | 0.020 | 1.310(1.044 – 1.642) | 0.016 | 1.319(1.052 – 1.654) |
| Hb (≥120 vs <120 gL-1) | 0.058 | 0.711(0.500 – 1.011) | 0.070 | 0.722(0.507 – 1.027) |
| Albumin (>40 vs ≤40 gL-1) | 0.021 | 1.340(1.045 – 1.718) | 0.044 | 1.292(1.007 – 1.658) |
| WBC count(≥6.685vs <6.685×103/μL) | 0.075 | 1.228(0.979 – 1.538) | 0.052 | 1.251(0.998 – 1.568) |
| PLT (≥300 vs <300 ×109L-1) | <0.001 | 1.698(1.332– 2.166) | <0.001 | 1.718(1.348 – 2.191) |
| MPV (≥11.0vs <11.0 fL) | <0.001 | 2.176(1.554– 3.046) | <0.001 | 2.220(1.585– 3.108) |
| D-dimer (>0.1vs ≤0.1 mgL-1) | 0.007 | 1.367(1.090–1.715) | 0.045 | 1.262(1.005– 1.584) |
| LDH (≥174vs <174UL-1) | 0.205 | 1.157(0.923 – 1.450) | 0.204 | 1.158(0.924– 1.451) |
| ALP (≥71vs <71UL-1) | 0.031 | 1.284(1.023 – 1.611) | 0.039 | 1.269(1.012 – 1.592) |
| Fibrinogen (≥3.543vs <3.543gL-1) | <0.001 | 1.059(1.241 – 1.960) | <0.001 | 1.580(1.257 – 1.985) |
| COP-MPV (0,1,2) | <0.001 | 1.841(1.558 – 2.174) | <0.001 | 1.859(1.574 – 2.196) |
Abbreviations: DFS, disease-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; SqCC, Squamous cell carcinoma; RDW, red blood cell distribution width; Hb, hemoglobin; WBC, white blood cell; PLT, platelet count; MPV, mean platelet volume; LDH, lactate dehydrogenase; ALP, alkaline phosphatase; COP-MPV, combination of preoperative platelet count and mean platelet volume.
P less than .05 is statistically significant.