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. 2017 Feb 1;8(9):15663–15676. doi: 10.18632/oncotarget.14933

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Copyright: © 2017 Hui et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Baseline levels of Klotho in the heart, kidney and liver were analyzed with immunoblotting and densitometric analysis. Lower levels of Klotho are evident in the heart and kidney of aging mice, but not in the liver. Relative Klotho deficiency in aging hearts is associated with lower levels of myocardial HSP70. Data are expressed as mean ± SE. n=6, *P<0.05 vs. adult.