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. 2017 Feb 1;8(9):15663–15676. doi: 10.18632/oncotarget.14933

Figure 5. Recombinant Klotho suppresses myocardial NF-κB activation in aging endotoxemic mice.

Figure 5

A. Myocardial NF-κB activation was assessed using TransAM NF-κB activity assay kit. Myocardial NF-κB activity is higher and NF-κB activation lasts longer in aging endotoxemic mice. Data are expressed as mean ± SE. n=8, *P<0.05 vs. control, #P<0.05 vs. adult. B. Treatment with recombinant Klotho after injection of LPS suppresses myocardial NF-κB activation. Data are expressed as mean ± SE. n=6, *P<0.05 vs. control, #P<0.05 vs. LPS+saline.