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. 2017 Feb 1;8(9):15663–15676. doi: 10.18632/oncotarget.14933

Figure 6. HSP70 suppresses LPS-induced NF-κB activation.

Figure 6

A. A representative immunoblot of 3 separate experiments shows that treatment with liposomal HSP70 dose-dependently increases cellular HSP70 levels in primary macrophages isolated from mouse peritoneal cavity. B. Representative immunofluorescence images of 3 separate experiments show that HSP70 (red, arrow) delivered into macrophages has a perinuclear distribution pattern and suppresses NF-κB (green) intranuclear translocation following LPS (0.2 μg/ml) stimulation. Objective 40x.