Figure 3. Kaplan-Meier estimates of.
A. progression-free survival (PFS) and B. overall survival (OS) of all patients according to EGFR mutation status. Patients with EGFR mutations showed significantly longer survival than those with wild-type EGFR or unknown EGFR mutation statuses (8.4 vs. 1.8 vs. 2.0 months, P < 0.001 for PFS; 23.5 vs. 13.1 vs. 6.7 months, P = 0.001 for OS). Nimotuzumab plus gefitinib was not found to have superior PFS compared with gefitinib monotherapy C. in patients with EGFR mutations (10.3 vs. 7.4 months in gefitinib alone, P = 0.42) or D. wild type EGFR patients (1.0 vs. 2.3 months in gefitinib alone, P = 0.85).