Fig. 1.

Presents the results of C18:1-ac versus C0/(C16:0-ac+C18:0-ac) of all subjects and patients ≥31 days of age, including the first (circles) and follow-up (triangles) samples of four patients with CPT-IA deficiency [n = 1,808 (1,803 + 5 follow-up samples)]. The numbers correspond to the case numbers presented in Table 2. The dashed lines indicate the 95% cut-off limits for C18:1-ac (0.05 μmol/L) and C0/(C16:0-ac+C18:0-ac) (587). The quadrant limited by C18:1-ac <0.05 μmol/L and C0/(C16:0-ac+C18:0-ac) >587 had a sensitivity of 100% and a specificity of 99.3% for diagnosis of CPT-IA deficiency in our study population