Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Multiple sequence alignment of H8 and its homologs. Identical and similar amino acids are shaded in black and gray, respectively. Stars indicate amino acid residues belonging to the catalytic triad, and circles indicate basic amino acid residues (Arg195, Arg203, Arg216, Arg236, and Arg263) selected for site-directed mutation. Sequence analysis suggested that residues Arg203, Arg216, and Arg236 are highly conserved, and residues Arg195 and Arg263 are partially conserved.
