Table 2.

Monoamine concentration levels (picomole/milligramme of tissue) in the prefrontal cortex, striatum, amygdala, nucleus accumbens and hippocampus in T+ and T− for Wistar rats (n = 11–14)

		5-HT	5-HIAA	5-HIAA/5-HT ratio	NE	DA
PFC	T+	1.67 ± 0.15	1.16 ± 0.14	0.70 ± 0.06	1.86 ± 0.14	1.68 ± 0.46
	T−	0.86 ± 0.09**	0.36 ± 0.03**	0.44 ± 0.03**	1.72 ± 0.13	2.87 ± 0.77
Striat	T+	3.56 ± 0.81	4.13 ± 0.88	1.17 ± 0.07	0.14 ± 0.03	130.64 ± 27.47
	T−	3.08 ± 0.47	2.08 ± 0.37*	0.65 ± 0.03**	0.22 ± 0.08	146.89 ± 23.26
Amyg	T+	2.93 ± 0.32	2.36 ± 0.22	0.83 ± 0.04	1.10 ± 0.21	18.89 ± 3.57
	T−	2.16 ± 0.21 #	1.01 ± 0.09**	0.48 ± 0.02**	1.47 ± 0.25	20.23 ± 2.83
NAc	T+	2.78 ± 0.75	2.50 ± 0.69	0.90 ± 0.02	2.50 ± 0.55	41.04 ± 13.00
	T−	2.61 ± 1.22	1.45 ± 0.59	0.62 ± 0.06**	5.73 ± 2.58	44.67 ± 20.58
Hippo	T+	1.23 ± 0.15	1.70 ± 0.22	1.38 ± 0.03	1.97 ± 0.20	1.11 ± 0.19
	T−	0.78 ± 0.10*	0.67 ± 0.05**	0.91 ± 0.04**	1.56 ± 0.11	1.72 ± 0.25

Data are mean ± SEM. Significant differences between T+ and T− (*p < 0.05, **p < 0.01, ^# p = 0.059)

PFC prefrontal cortex, NAc nucleus accumbens, Amyg amygdala, Striat striatum, Hippo hippocampus