Table 3.

Monoamine concentration levels (picomole/milligramme of tissue) in the prefrontal cortex, striatum, amygdala, nucleus accumbens and hippocampus in T+ and T− for Lister Hooded rats (n = 4–9)

		5-HT	5-HIAA	5-HIAA/5-HT ratio	NE	DA
PFC	T+	1.77 ± 0.09	1.02 ± 0.09	0.56 ± 0.04	1.62 ± 0.09	3.89 ± 1.08
	T−	0.99 ± 0.11**	0.04 ± 0.07**	0.35 ± 0.07**	1.31 ± 0.08*	2.34 ± 0.72
Striat	T+	2.20 ± 0.27	1.98 ± 0.31	0.88 ± 0.04	0.25 ± 0.07	79.35 ± 11.61
	T−	0.92 ± 0.15**	0.52 ± 0.06**	0.60 ± 0.06**	0.22 ± 0.08	83.19 ± 7.21
Amyg	T+	2.81 ± 0.32	2.12 ± 0.21	0.78 ± 0.05	1.38 ± 0.28	12.94 ± 2.56
	T−	1.75 ± 0.21*	0.68 ± 0.09**	0.39 ± 0.02**	1.13 ± 0.34	20.18 ± 3.28
NAc	T+	2.74 ± 0.31	2.34 ± 0.19	0.90 ± 0.06	8.01 ± 1.98	23.14 ± 4.36
	T−	2.09 ± 0.22	1.01 ± 0.15**	0.48 ± 0.02**	3.40 ± 1.96	48.99 ± 9.52*
Hippo	T+	1,45 ± 0.19	2.17 ± 0.24	1.54 ± 0.07	2.60 ± 0.23	4.95 ± 1.71
	T−	0.79 ± 0.07**	0.64 ± 0.07**	0.81 ± 0.06**	3.05 ± 0.62	9.45 ± 3.46

Data are mean ± SEM. Significant differences between T+ and T− (*p < 0.05, **p < 0.01)

PFC prefrontal cortex, NAc nucleus accumbens, Amyg amygdala, Striat striatum, Hippo hippocampus