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. 2017 Apr;24(4):145–152. doi: 10.1101/lm.043000.116

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© 2017 Criado-Marrero et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 6. — Reducing IL FKBP5 after fear conditioning facilitates extinction recall. (A) Timeline for behavioral training after IL infusion of Fkbp5-shRNA or control (scramble) plasmids 5 d prior to EXT. (B) IL cannula placement for scramble (black dots) and Fkbp5-shRNA (red dots) rats and GFP expression. (C) Freezing of rats infused with Fkbp5–shRNA or scramble plasmid into IL prior extinction. (D) Average freezing of IL-infused rats to two recall tones on day 9. n = 9–13 for each group, (*) P < 0.05.