Figure 7.
Reducing FKBP5 in PL does not affect fear conditioning or extinction. (A) Cannula placement for scramble (black dots) and Fkbp5–shRNA (red dots) rats. (B) Localized expression of GFP in PL 5 d after bilateral infusion of Fkbp5–shRNA plasmid. (C) Freezing of rats infused with Fkbp5–shRNA or scramble plasmid into PL. (D) Average freezing of PL-infused rats to two recall tones on day 3. n = 10–12 for each group, unpaired t-test P > 0.05.