Table 2.
mRNAs expressed in MSC-EVs.
| Source of EVs | mRNA | Function | Reference |
|---|---|---|---|
| Human bone marrow-derived MSCs | IGF-1R | Enhance cell proliferation | [46] |
| Human bone marrow-derived MSCs | RAX2, OR11H12, OR2M3, DDN, GRIN3A, NIN, BMP15, IBSP, MAGED2, EPX, HK3, COL4A2, CEACAM5, SCNN1G, PKD2L2, | Involved in cell differentiation | [47] |
| Human bone marrow-derived MSCs | CLOCK, IRF6, RAX2, TCFP2, BCL6B | Involved in transcription | [47] |
| Human bone marrow-derived MSCs | HMGN4, TOPORS, ESF1, ELP4, POLR2E, HNRPH2 | DNA/RNA binding | [47] |
| Human bone marrow-derived MSCs | SENP2, RBL1, CDC14B, S100A13 | Cell cycle | [47] |
| Human bone marrow-derived MSCs | CEACAM5, CLEC2A, CXCR7 | Receptors | [47] |
| Human bone marrow-derived MSCs | ADAM15, FUT3, ADM2, LTA4H, BDH2, RAB5A | Involved in metabolism | [47] |
| Human bone marrow-derived MSCs | CRLF1, IL1RN, MT1X | Immune regulation | [47] |
| Human bone marrow-derived MSCs | DDN, MSN, CTNNA1 | Cytoskeleton | [47] |
| Human bone marrow-derived MSCs | COL4A2, IBSP | Extracellular matrix | [47] |
| Porcine adipose tissue-derived MSCs | FOXP3, JMJD1C, KDM6B | Encode transcription factors involved in chromosome organization | [48] |
| Porcine adipose tissue-derived MSCs | MDM4, IFT57, PEG3, PDCD4 | Encode transcription factors involved in apoptosis | [48] |
| Porcine adipose tissue-derived MSCs | HGF, HES1, TCF4 | Encode transcription factors involved in proangiogenic pathways | [48] |
| Porcine adipose tissue-derived MSCs | ZBTB1, ZNF217, ZNF238, ZNF461, ZNF568, ZNF667, ZHX1 | Encode zinc-finger transcription factors | [48] |
| Porcine adipose tissue-derived MSCs | TMF1, BAZ2B, JMJD1C, MYNN, NFKBIZ, PEG3, KCNH6, RUNX1T1, SUFU | Encode transcription factors involved in alternative splicing | [48] |