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. 2016 Jan 21;59(3):1078–1101. doi: 10.1021/acs.jmedchem.5b01685

Scheme 1. General Synthetic Routes to 3,4,5-Trisubtituted Pyridines.

Scheme 1

The asterisk (∗) indicates different solvent and/or slightly different conditions were used for compounds 17, 18, 42, 47, 50, and 52.