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| species | Cl (L/h/kg) | LBF (%) | Vd (L/kg) | F (%) | t1/2 (h) |
|---|---|---|---|---|---|
| mouse | 0.61 | 10 | 0.63 | 30 | 0.78 |
| rat | 1.49 | 34 | 2.0 | 57 | 1.10 |
| dog | 1.07 | 43 | 1.4 | 68 | 0.99 |
| human prediction | ∼0.36 | ∼31 | ∼1.4 | ∼70 | ∼2.7 |
Dose: 0.2 mg/kg (iv), 0.5 mg/kg (po).
