Table 2. Association of PD-L1 and PD-1 Genotypes with Clinical Response.

	Gene	Location	Ancestral allele	No. of Patients	Clinical Response (ORR)
					No.	%	P†
rs1411262	PD-L1	intron	T				0.0751
T/T				15	4	24
T/C				21	3	14
C/C				14	1	7
rs2282055	PD-L1	intron	T				0.0339
T/T				10	0	0
T/G				20	3	15
G/G				20	5	25
rs4143815	PD-L1	3′ UTR	G				0.0319
G/G				12	0	0
G/C				23	4	17
C/C				15	4	27
rs2890658	PD-L1	intron	C				0.2088
C/C				33	6	18
C/A				14	2	14
A/A				3	0	0
rs822339	PD-L1	intron	G				0.0855
G/G				14	1	7
G/A				21	3	14
A/A				15	4	27
rs2227981	PD-1	synonymous	G				0.1428
G/G				26	3	12
G/A				21	4	19
A/A				3	1	33
rs2227982	PD-1	missense	G				0.3628
G/G				15	4	27
G/A				22	1	5
A/A				13	3	23

Abbreviations: ORR, objective response rate; ^†Exact test of Cochran-Armitage trend test across genotypes.