Figure 2.

Means +/− SEM SCID male mice with out without splenocytes replacement versus control B6 mice in social preference (a) and social recognition tasks (b). a) In the social preference task SCID mice that receive splenocytes have lower preference scores than SCID mice that receive saline (*p<0.05). b) SCID mice have impaired social recognition that is ameliorated with splenocyte transfer. All groups habituated to a stimulus mouse over 8 trials (**p<0.001). Only B6 and SCID mice with splenocyte transfer dishabituated on trial 9 (***p<0.001). SCID+splenocytes N=12, SCID+saline N=12, B6 N=14