Table 1.

Haematological, biochemical and serological results obtained before, during and after treatment

	Day 0	Day 45	Month 6	Month 12	Month 18	Month 24	Reference intervals
Haemogram
Leukocytes (×10³/µl)	13.3	15.0	10.0	NA	NA	15.6	5.5–19.5
Erythrocytes (×106/µl)	6.6	9.2	10.2	NA	NA	9.5	5.0–10.0
Platelets (×10³/µl)	185	327	129	NA	NA	223	300–700
Haemoglobin (g/dl)	9	12	14	NA	NA	13	8–15
PCV (%)	29	40	40	NA	NA	43	24–45
Non-segmented neutrophils (/µl)	0	0	0	NA	NA	0	0–300
Segmented neutrophils (/µl)	9.520	11,000	6.468	NA	NA	7.000	2.500–12.500
Lymphocytes (/µl)	2.856	3000	2.980	NA	NA	2.800	1.500–7.000
Monocytes (/µl)	0.5	0.3	0.1	NA	NA	4.7	0–850.0
Eosinophils (/µl)	0.680	0.600	0.390	NA	NA	0	0–1.500
Basophils (/µl)	0	0	0	NA	NA	0	Rare
Biochemical parameters
Urea (mg/dl)	48.7	52.9	50.0	NA	52.3	59.9	0–82.0
Creatinine (mg/dl)	0.73	0.97	1.07	NA	1.23	1.25	0.70– 2.20
ALT (U/l)	37	37	35	NA	45	37	10–130
AST (U/l)	NA	NA	NA	NA	28	28	8–35
Alkaline phosphatase (U/l)	NA	NA	43	NA	21	32	20–220
Calcium (mmol/l)	NA	NA	NA	NA	9.52	8.92	9.40–11.20
Total bilirubin (mg/dl)	NA	NA	NA	NA	0.06	0.05	0.08–0.30
Potassium (mmol/l)	NA	NA	NA	NA	4.4	4.8	3.5–5.2
Chloride (mmol/l)	NA	NA	NA	NA	123	137	108–128
Sodium (mmol/l)	NA	NA	NA	NA	156	156	143–153
Biliary acids (µmol/l)	NA	NA	NA	NA	3.68	3.53	1–20.00
Inorganic phosphorus (mmol/l)	NA	NA	NA	NA	4.4	4.8	2.4–6.0
Urinary protein: creatinine ratio (%)	NA	NA	0.04	NA	NA	NA	<0.50
Serum protein electrophoresis
Total protein (g/dl)	6.9	7.1	6.8	NA	7.2	NA	5.7–7.9
Albumin (g/dl)	2.6	2.7	3.1	NA	3.2	NA	2.1–4.0
Alpha 1 (g/dl)	0.4	0.1	0.1	NA	0.1	NA	0.2–1.1
Alpha 2 (g/dl)	1.1	1.4	1.6	NA	1.7	NA	0.4–0.9
Beta (g/dl)	0.4	1.1	0.9	NA	1.1	NA	0.9–1.9
Gama (g/dl)	2.4	1.9	1.1	NA	1.1	NA	1.3–2.2
Albumin: globulin ratio (%)	0.60	0.60	0.90	NA	0.80	NA	0.45–1.30
Antibody titre (IFAT)
Anti-Leishmania antibodies	⩾1:1280	1:320	1:80	1:80	1:40	1:40

PCV = packed cell volume; ALT = alanine aminotransferase; AST = aspartate aminotransferase; NA = not available