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. 2017 Mar 23;7:45072. doi: 10.1038/srep45072

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Dynamic bioprocess strategies (A,C,E) and respective resulting q_s,glu/q_s,lac,max-correlations (B,D,F) for the pET-based recombinant E. coli BL21(DE3) strain producing the tandem scFv against celiac disease. Different feeding phases are marked by different symbols. Time courses within phases go from light grey to dark grey, as indicated on the left. The shape and colour of the symbols of the q_s,glu/q_s,lac,max data points on the right (B,D,F) correspond to the symbols on the left (A,C,E). Samples were taken every hour during adaptation, every 10 min during q_s,glu ramps and every hour after the ramp. For clear data representation error bars were omitted. The error was always between 7% and 15%.