Table 2.

Evaluation of nephrotoxic compounds in HK-2 and SA7K Cells.

Compounds	Cell viability (IC50, µM)		Caspase 3/7 (EC50, µM)		MMP (IC50, µM)
	HK-2	SA7K	HK-2	SA7K	HK-2	SA7K
Camptothecin	0.69±0.09	0.75±0.14	0.47±0.05	1.92$\pm$0.54	6.26±0.51	14.54±3.63
Sunitinib malate	18.03±3.09	12.65±3.06	Inactive	7.33±1.78	Inactive	Inactive
Sulfinpyrazone	22.21±1.81	Inactive	Inactive	Inactive	14.82±1.28	11±4.15
Mitomycin C	10.11±0.66	7.53±2.90	23.79±4.44	6.38±0.42	Inactive	Inactive
Vinblastine Sulfate	Inactive	Inactive	Inactive	0.57±1.86	Inactive	Inactive
Doxorubicin	3.89±0.50	2.51±0.74	2.64±0.79	2.75±0.35	0.39±0.19	1.18±0.51
Taxol	Inactive	Inactive	0.04±0.01	0.67±0.29	34.08±4.45	35.87±2.34
Ochratoxin A	0.04±0	17.00±1.38	0.15±0.06	Inactive	Inactive	Inactive
Ergotamine	Inactive	Inactive	Inactive	Inactive	17.64±1.43	16.16±2.75
Digoxin	0.03±0.008	0.61±0.19	Inactive	Inactive	Inactive	Inactive

Data are presented as mean ± SD from two to three experiments.