Table 3.
Sensitivity and specificity values of various analysis methods and databases compared with clinical diagnosis.
| Ethnic-specific Database | With Borderline Considered as Normal | With Borderline Considered as Abnormal | |||||
|---|---|---|---|---|---|---|---|
| AUC (95% CI) |
Sensitivity (%) | Specificity (%) | AUC (95% CI) |
Sensitivity (%) | Specificity (%) | ||
| MRA | |||||||
| Caucasian | 0.77 (0.67, 0.88) |
68 | 87 | 0.83 (0.74, 0.91) |
88 | 77 | |
| African- American |
0.79 (0.69, 0.89) |
68 | 90 | 0.79 (0.70, 0.89) |
80 | 79 | |
| Indian | 0.73 (0.63, 0.84) |
52 | 94 | 0.80 (0.70, 0.90) |
76 | 85 | |
| GPS | |||||||
| Caucasian | 0.76 (0.66, 0.87) |
68 | 85 | 0.70 (0.61, 0.79) |
88 | 52 | |
| African- American |
0.77 (0.67, 0.87) |
56 | 98 | 0.77 (0.67, 0.88) |
72 | 83 | |
| Indian | 0.76 (0.66, 0.87) |
68 | 85 | 0.70 (0.61, 0.79) |
88 | 52 | |
MRA: Moorfields Regression Analysis; GPS: Glaucoma Probability Score; AUC: Area Under Curve.