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. 2017 Mar 23;7:44723. doi: 10.1038/srep44723

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Copyright © 2017, The Author(s)

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(A) Survival curve of GRP78 heterozygous (GRP78^+/−) and wild type (GRP78^+/+) mice intra-cerebrally inoculated with RML prions. Differences in animal survival were analyzed by the Log-rank (Mantel Cox) test and found highly significant (P = 0.0018). (B) Average incubation periods of the different groups showed in panel A. Data is expressed as averages ± standard errors. Differences among the groups were analyzed by student’s t-test. ***P < 0.001.