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. 2017 Feb 9;25(3):593–605. doi: 10.1016/j.ymthe.2017.01.019

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Profile of the Virus Integration Site in Mouse Bone Marrow Genomic DNA after Transduction with the γ-Globin/NA10HD Vector

(A) The locations of 715 virus integration sites related to the gene: the percentages of total integration sites within 20 kb upstream of transcript start sites, within genes, and within 50 kb of oncogenes or tumor suppressor genes were plotted against three size-matched sets of computer-generated random sites. (B) Ontologies of genes within 50 kb of integration sites compared with size-matched set of genes within 50 kb of random generated sites, using the DAVID functional annotation tool.