Figure 1.

Inhibition of factor Xa by the ligation product of phenyl ester 12 (A) or 2,2,2‐trifluoroethyl ester 13 (B; both 5 mm) with 4‐aminomethylbenzamidine (14; 0.285 mm). Blue: templated reaction; red: non‐templated reaction. A mixture of carboxylic acid 1 and amine 14 was used as negative control.