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. Author manuscript; available in PMC: 2017 Mar 23.
Published in final edited form as: Exp Neurol. 2015 Mar 13;267:115–122. doi: 10.1016/j.expneurol.2015.03.004

Fig. 3.

Fig. 3

Direct treatment of A2aR antagonist significantly protects ESMNs from SOD1G93A+ astrocyte-induced cell death. A. A representative image of ESMNs following A2aR antagonist KW6002 treatment in ESMN and SOD1G93A+ astrocyte co-cultures. B. Immunostaining of βIII-tubulin in astrocyte and ESMN co-cultures following KW6002 treatment. C. The quantification of ESMNs following A2aR antagonist KW6002 treatment in ESMN and SOD1G93A+ astrocyte co-cultures. ***, P < 0.001, *, P < 0.05 from one-way ANOVA test and Bonferroni post-test; astro.: astrocytes. N = 264–418 neurons from three independent experiments.