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. Author manuscript; available in PMC: 2017 Mar 23.

Published in final edited form as: Exp Neurol. 2015 Mar 13;267:115–122. doi: 10.1016/j.expneurol.2015.03.004

Fig. 6 — Partial genetic ablation of A_2aR significantly delays disease progression in SOD1G93A mice. Longitudinal forelimb grip strength change between A_2aR^+/+ SOD1G93A⁺ and A_2aR^−/−SOD1G93A⁺ (A, P = 0.77), A_2aR^+/+ SOD1G93A⁺ and A_2aR^+/− SOD1G93A⁺ (B, P = 0.03). Survival curves of A_2aR^+/+SOD1G93A⁺, A_2aR^+/− SOD1G93A⁺ mice (C, P = 0.04, Log-rank test) and A_2aR^+/+ SOD1G93A⁺, A_2aR^−/−SOD1G93A⁺ mice (D, N.S.: not significant); N = 11–15 mice/group.