Table 4.

Characteristics of KTE-C19 Products

	Patient No.
	1	2	3	4	5	6	7
CAR T cells/kg × 106	2.0	2.0	2.0	1.1	2.0	1.9	1.2
CD4 T cells (%)	18	73	30	34	51	30	68
CD8 T cells (%)	82	27	70	66	49	70	32
CD8/CD4 T cell ratio	4.6	0.4	2.3	1.9	1	2.3	0.5
IFN-γ production in co-culture (pg/mL)a	20,930	8,589	3,356	7,598	6,948	2,278	816
Manufacturing time (days)	8	8	8	8	8	9	8

^aCo-culture experiments were performed using Toledo cells mixed in a 1:1 ratio with KTE-C19 product cells. IFN-γ was measured in cell culture media 24 hr post-incubation using a qualified ELISA.