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. 2017 Jan 4;25(1):153–164. doi: 10.1016/j.ymthe.2016.10.002

Figure 1.

Figure 1

Immunization Design of Tg2576 Mice and Humoral Immune Responses Specific to Amyloid

(A) Preventive study: 6–6.5-month-old Tg2576 mice (n = 8) were immunized with adjuvanted EV. Control mice were injected with adjuvant alone (n = 6). (B) Therapeutic study: 16–19-month-old Tg2576 mice (n = 6) were immunized with adjuvanted EV. Control mice were injected with adjuvant alone (n = 5). (C and D) Concentrations of anti-Aβ antibodies in sera of EV immunized Tg2576 mice in preventive (C) and therapeutic (D) studies analyzed by ELISA.