Skip to main content
. 2017 Jan 4;25(1):153–164. doi: 10.1016/j.ymthe.2016.10.002

Figure 6.

Figure 6

AD-like Pathology in the Hemibrain Cortical or Hippocampal Regions of 15–15.5-Month-Old Tg2576 Mice with or without Pre-existing Memory Th Cells Vaccinated with EV

(A and C) Aβ load in the hemibrain cortical (A) and hippocampal (C) regions of vaccinated mice with pre-existing memory Th cells (n = 8) and age-matched control animals (n = 9), and vaccinated mice without pre-existing memory Th cells (n = 5). (B and D) ThS-positive core Aβ plaques in the hemibrain cortical (B) and hippocampal (D) regions of vaccinated mice with pre-existing memory Th cells (n = 8) and age-matched control animals (n = 9), and vaccinated mice without pre-existing memory Th cells (n = 5). Photomicrographs show representative images of hemibrain regions of immunized and control mice. Scale bars, 100 μm (A and B) and 200 μm (C and D). Error bars represent average ± SD (∗p < 0.05).