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. 2016 Dec 24;4:50–61. doi: 10.1016/j.omtm.2016.11.004

Figure 4.

Figure 4

Anti-CD163-Dexamethasone Treatment Strongly Reduces Development of Steatohepatitis and Fibrosis in Rats on the HFr Diet

Treatment effects of free dexamethasone, anti-CD163-dexamethasone, and IgG-dexamethasone conjugates. The left panel represents H&E staining showing fat depositions, inflammation, and hepatocyte ballooning. The right panel represents Masson’s trichrome-stained sections showing hepatic regions with fibrosis (blue staining represents collagen deposition). Magnification, ×20. Scale bars represent 200 μm.