Table 4.

Gene Expression Similarities Between TC (Tibial Compression) and DMM (Destabilization of Medial Meniscus) at Various Time Points Post Injury

Time Point	TC
	1 Day (496)		1 Week (514)		6 Weeks (370)		12 Weeks (174)
	No. Genes	% Genes	No. Genes	% Genes	No. Genes	% Genes	No. Genes	% Genes
DMM up‐regulated transcripts
1 week (C)	n/c		67	13.04	n/c		n/c
2 weeks (C)	n/c		139	27.04	n/c		n/c
2 weeks (WJ)	168	33.87	228	44.36	68	18.38	26	14.94
4 weeks (WJ)	262	52.82	382	74.32	125	33.78	36	20.69
6 weeks (C)	n/c		n/c		32	8.65	n/c
16 weeks (WJ)	21	4.23	41	7.98	28	7.57	14	8.05

	1 Day (103)		1 Week (130)		6 Weeks (141)		12 Weeks (27)
	No. Genes	% Genes	No. Genes	% Genes	No. Genes	% Genes	No. Genes	% Genes
DMM down‐regulated transcripts
1 week (C)	n/c		4	3.08	n/c		n/c
2 weeks (C)	n/c		17	13.08	n/c		n/c
2 weeks (WJ)	5	4.85	6	4.62	1	0.71	0	0.00
4 weeks (WJ)	9	8.74	6	4.62	1	0.71	0	0.00
6 weeks (C)	n/c		n/c		4	2.84	n/c
16 weeks (WJ)	0	0.00	0	0.00	0	0.00	0	0.00

C, cartilage (Bateman et al.)¹⁷; WJ, whole joint (Loeser et al.)¹⁸; n/c comparison was not conducted.

Number of overlapping genes are presented as the net number of genes up‐ (a) or down‐ (b) regulated in both the TC and DMM datasets, as well as percentage of the entire gene expression data set described for the TC time points.