Table 1.
Overlap between annotation made on the co‐expression clusters derived from network analysis of the RNA‐seq and microarray datasets
| Cluster annotation | RNA‐seq‐specific | Microarray‐specific | SkinSig (No. of genes) | % Common (relative to the RNA‐seq dataset) | % Common (relative to the microarray dataset) |
|---|---|---|---|---|---|
| Hair follicle | 76 | 10 | 62 | 45% | 86% |
| Sebaceous gland | 17 | 229 | 105 | 86% | 31% |
| Eccrine sweat gland | 62 | 79 | 101 | 62% | 56% |
| Apocrine gland | 25 | 0 | 25 | Dataset‐specific | |
| Keratinocyte differentiation | 48 | 114 | 78 | 62% | 41% |
| Keratinocyte (subset) | 4 | 4 | 7 | 64% | 64% |
| Melanocyte | 1 | 10 | 7 | 88% | 41% |
| Fibroblast | 69 | 160 | 132 | 66% | 45% |
| Endothelium | 150 | 18 | 40 | 21% | 69% |
| Smooth muscle | 49 | 19 | 49 | 50% | 72% |
| Skeletal muscle | 64 | 0 | 64 | Dataset‐specific | |
| Adipocyte | 10 | 21 | 30 | 75% | 59% |
| Macrophage/DC | 45 | 39 | 49 | 52% | 56% |
| T cell | 29 | 13 | 17 | 37% | 57% |
| FcϵR signalling | 9 | 0 | 7 | 44% | 100% |
| Plasma cell | 2 | 17 | 7 | 78% | 29% |
| IFN | 21 | 5 | 22 | 51% | 81% |
| Cell cycle (S/M) | 69 | 8 | 65 | 49% | 89% |
| Circadian clock | 0 | 8 | 8 | Dataset‐specific | |
| Y‐chromosome | 3 | 1 | 13 | 81% | 93% |