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. 2016 Dec 10;6:45–56. doi: 10.1016/j.omtn.2016.11.002

Figure 5.

Figure 5

Ant-134 Delays Epileptiform Activity Onset in Ex Vivo Slices in Response to 9 mM K+

(A) Schematic of experimental design. Rats were injected with Ant-134 or control 2–4 days prior to ex vivo slice preparation. Local field potential recordings were made in hippocampal CA1. (B) Bar chart shows that epileptiform activity onset was delayed by Ant-134 (**p = 0.002, α = 0.025; statistical power = 0.87, Mann-Whitney U test; control, n = 9 slices from 3 rats; Ant-134, n = 11 slices from 3 rats). (C) Representative traces of epileptiform activity elicited by 9 mM K+ in slices from control or Ant-134-treated rats. All error bars shown as means ± SEM.