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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Synapse. 2016 Nov 30;71(3):10.1002/syn.21950. doi: 10.1002/syn.21950

FIGURE 5.

FIGURE 5

In Vitro 18F-7-OH-FHXPAT Studies. In vitro autoradiographs of rat brain horizontal slices (10 μm thick) incubated with 111 kBq/cc at 37°C, showing (a). Total binding of 18F-7-OH-FHXPAT. (b). Binding of 18F-7-OH-FHXPAT in the presence of 10 μM SKF10047 (55% binding was reduced over the various brain regions). (c). Binding of 18F-7-OH-FHXPAT in the presence of SKF10047 and dopamine (56% of the striatal binding was reduced) and (d). Nonspecific binding of 18F-7-OH-FHXPAT in the presence of 10 μM haloperidol (>95% binding of 18F-7-OH-FHXPAT was displaced)