Figure 3.

Inhibition of striatal neurons reduced the atrophy volume and promoted motor recovery after cerebral ischemia. (a) Cresyl violet staining of brain slice at 35 days after tMCAO surgery. Dash line indicted the atrophic tissues. (b) Mice showed smaller brain atrophy volume in the inhibition group and larger atrophy volume in excitation group compared to the control.* represents p < 0.05, n = 7. (c) Average speed of mice in the open field test at each time point. Mice in the inhibition group moved faster compared to the control, * represents p < 0.05, n = 7. (d) Duration of time in Rotarod test at each time point. Mice in the inhibition group persisted for longer time on the rotating rod compared to the control, ** represents p < 0.01, n = 7.