Table 2.

List of clinical outcomes stratified by perilesional hyperperfusion (PLH).

	All patients	PLH	No PLH
	n = 119	n = 42	n = 77	Pa
24 h core volume (in ml); median (IQR)	22.4 [61.1]	16.2 [33.1]	35.3 [63.7]	0.1413
Median 24 h NIHSS (IQR) (n = 153)	7 (11)	6 (8)	7.5 (13)	0.0850
Any penumbral salvage
Yes	68 (57.14)	32 (76.19)	36 (46.75)	0.002*
No	51 (42.86)	10 (23.81)	41 (53.25)	0.002*
Penumbral salvage volume (in ml)
Median (IQR)	9.9 [91.9]	22.75 [68.9]	−6.8 [103.4]	0.0277*
Mean ± SD	10.33 ± 65.87	22.23 ± 71.65	3.83 ± 62.01	0.0277*
Reperfusion status				0.002*
Major reperfusion	71 (59.66)	34 (80.95)	37 (48.05)	<0.0001*
Incomplete reperfusion	15 (12.61)	3 (7.14)	12 (15.58)	0.252
No reperfusion	35 (29.41)	5 (11.9)	30 (38.96)	0.002*
HT	8 (6.9)	7 (16.67)	1 (1.35)	0.003*
HI1 or HI2	7 (6.03)	7 (16.67)	0 (0)	0.001*
PH1 or PH2	1 (0.86)	0	1 (1.35)	1.000
Major petechial (>5 mm)	94 (81.03)	33 (78.57)	61 (82.43)	0.629
Minor petechial (<5 mm)	109 (93.97)	40 (95.24)	69 (93.24)	1.000
ENI (ΔNIHSS ≥ 8 or ΔNIHSS < 2)	53 (44.92)	24 (58.54)	29 (37.66)	0.034*
END (ΔNIHSS≤−4)	5 (4.24)	0 (0)	5 (6.49)	0.162
Median 90 days mRS (IQR)	2 (3)	2 (2)	2 (4)	0.1775
Good (mRS = 0–2)	66 (55.46)	26 (61.9)	40 (51.95)	0.338
0	23 (19.33)	8 (19.05)	15 (19.48)	1.000
1	23 (19.33)	11 (26.19)	12 (15.58)	0.224
2	20 (16.81)	7 (16.67)	13 (16.88)	1.000
Bad (mRS = 3–6)	53 (44.54)	16 (38.1)	37 (48.05)	0.338
3	15 (12.61)	6 (14.29)	9 (11.69)	0.775
4	13 (10.92)	5 (11.90)	8 (10.39)	0.769
5	14 (11.76)	4 (9.52)	10 (12.99)	0.768
6	11 (9.24)	1 (2.38)	10 (12.99)	0.094

END: early neurological deterioration; ENI: early neurological improvement; HT: haemorrhagic transformation; mRS: modified Rankin score.

The clinical outcome at 90 days was assessed using mRS (score range: 0–6), where an mRS score of 0–2 corresponds to a good outcome.

Figures in parentheses are percentages or interquartile range (IQR).

^*P < 0.05 as the threshold for statistical significance.

^aUncorrected for multiple comparisons.