Figure 7.

The Change on Important Organs and Tissues in Nude Mice Model of Human Lung Cancer

Human lung cancer cell line 95D cells were injected subcutaneously into right flank of BALB/c nude mice (n = 8). 7 days later, the plasmid of p-T-miR-7 (100 mg) or p-Cont (100 mg) was remotely given by subcutaneous injection into the left flank of nude mice five times every three days. 3 days after last injection, all of the mice were sacrificed. (A) The morphology and H&E staining of various organs and tissues, including heart, liver, spleen, kidney, brain and lymph nodes, were performed. (B) The weight of indicated organs and tissues also were obtained. (C) The concentration of the serum AST and ALT were measured, respectively. NS, no significance.