Skip to main content
. 2016 Dec 31;6:259–268. doi: 10.1016/j.omtn.2016.12.009

Figure 4.

Figure 4

Effect of AKSLHNs on Lung Tumor Inhibition

(A) In vivo evaluation of siRNA nanoparticles in lung tumor-bearing SCID beige mice. IVIS bioluminescence was used for imaging. ***p ≤ 0.001, n = 3. Error bars are ± SD. (B) Determination of apoptosis in lung tumors using cell death detection ELISA after various treatments in SCID beige mice models. Nano represents AKSLHNs, whereas combination represents AKSLHNs in combination with erlotinib. **p ≤ 0.01; ****p ≤ 0.0001 (n = 3). Error bars are ± SD. (C) TUNEL analysis of apoptosis in lung tissue sections from variously treated groups; from left to right: AKSLHNs, erlotinib, combination of AKSLHNs and erlotinib, and PBS treatment.