Table 1. General characteristics of WT and ALDH2 mice fed starch or sucrose diet.
WT-Starch | WT-Sucrose | ALDH2-Starch | ALDH2-Sucrose | |
---|---|---|---|---|
Body Weight (g) | 28.8 ± 0.6 | 30.9 ± 1.1 | 30.1 ± 0.8 | 31.2 ± 0.8 |
Heart Weight (mg) | 130 ± 3 | 141 ± 3 | 127 ± 4 | 138 ± 4 |
Heart/Body Weight (mg/g) | 4.53 ± 0.15 | 4.57 ± 0.13 | 4.24 ± 0.10 | 4.44 ± 0.05 |
Liver Weight (g) | 1.19 ± 0.04 | 1.24 ± 0.04 | 1.21 ± 0.04 | 1.25 ± 0.05 |
Kidney Weight (g) | 0.35 ± 0.02 | 0.37 ± 0.01 | 0.34 ± 0.01 | 0.34 ± 0.01 |
Heart Rate (bpm) | 473 ± 12 | 467 ± 7 | 476 ± 12 | 474 ± 16 |
LV Wall Thickness (mm) | 0.96 ± 0.08 | 0.95 ± 0.05 | 0.89 ± 0.08 | 0.93 ± 0.07 |
LVEDD (mm) | 2.33 ± 0.16 | 2.49 ± 0.11 | 2.26 ± 0.13 | 2.25 ± 0.13 |
LVESD (mm) | 1.04 ± 0.12 | 1.55 ± 0.19* | 0.91 ± 0.11 | 0.95 ± 0.10# |
Fractional Shortening (%) | 54.6 ± 1.5 | 43.0 ± 2.1* | 56.6 ± 1.5 | 53.3 ± 3.1# |
LV, left ventricular; EDD, end-diastolic diameter; ESD, end-systolic diameter, Mean ± SEM, n = 6-7 mice per group,
p < 0.05 vs. WT-Starch group,
p < 0.05 vs. WT-Sucrose group.