Table 1. Influence of the amount of stannous chloride on the labeling efficiency of NPs.
SnCl2·2H2O (μg) | 20 | 30 | 50 | 100 | |
---|---|---|---|---|---|
K237/FA-PEG-PLGA (LA/GA = 60/40) | |||||
% Labeled (mean ± SD) | 97.95 ± 1.13 | 95.88 ± 2.73 | 94.3 ± 1.90 | 86.92 ± 2.85 | |
% colloids (mean ± SD) | 0.37 ± 0.35 | 1.16 ± 0.87 | 1.77 ± 0.55 | 2.71 ± 1.83 | |
% free (mean ± SD) | 1.68 ± 0.44 | 2.96 ± 1.07 | 3.93 ± 1.61 | 10.37 ± 3.32 | |
K237/FA-PEG-PLGA (LA/GA = 70/30) | |||||
% Labeled (mean ± SD) | 96.56 ± 3.66 | 94.12 ± 3.12 | 93.58 ± 3.16 | 84.12 ± 3.24 | |
% colloids (mean ± SD) | 1.08 ± 0.36 | 2.03 ± 0.82 | 2.37 ± 1.00 | 4.06 ± 2.75 | |
% free (mean ± SD) | 2.36 ± 1.42 | 3.75 ± 1.28 | 4.05 ± 0.78 | 11.82 ± 2.47 | |
K237/FA-PEG-PLGA (LA/GA = 80/20) | |||||
% Labeled (mean ± SD) | 95.40 ± 2.29 | 94.39 ± 1.93 | 93.26 ± 3.19 | 82.98 ± 2.70 | |
% colloids (mean ± SD) | 1.73 ± 0.72 | 2.099 ± 0.54 | 2.56 ± 0.82 | 4.75 ± 2.50 | |
% free (mean ± SD) | 2.87 ± 0.72 | 3.52 ± 1.86 | 4.18 ± 2.04 | 12.27 ± 3.43 |