Table 2. Frequency distributions of alleles and their associations with cervical cancer.
SNP | Chromosome | Band | Gene (s) | Alleles A/B | MAF (case) | MAF (control) | HWE-P | OR (95% CI) | P |
---|---|---|---|---|---|---|---|---|---|
rs1048512 | 1 | 1q23.2 | PIGM | A/G | 0.099 | 0.112 | 0.23 | 0.87 (0.59–1.29) | 0.489 |
rs6659346 | 1 | 1q23.2 | PIGM | A/G | 0.111 | 0.118 | 0.15 | 0.94 (0.64–1.37) | 0.751 |
rs11006369 | 10 | 10q11.23 | SGMS1 | T/A | 0.121 | 0.093 | 0.72 | 1.35 (0.91–1.99) | 0.133 |
rs2862833 | 10 | 10q23.31 | FAS | G/A | 0.490 | 0.456 | 0.15 | 1.14 (0.90–1.46) | 0.272 |
rs3741216 | 11 | 11p15.5 | H19 | A/T | 0.077 | 0.074 | 0.38 | 1.05 (0.66–1.65) | 0.842 |
rs217727 | 11 | 11p15.5 | H19 | A/G | 0.315 | 0.231 | 0.74 | 1.53 (1.17–2.02) | 0.002 |
rs2839702 | 11 | 11p15.5 | H19 | C/A | 0.356 | 0.384 | 0.13 | 0.88 (0.69–1.44) | 0.337 |
rs2067051 | 11 | 11p15.5 | MIR675 | T/C | 0.336 | 0.376 | 0.10 | 0.84 (0.65–1.08) | 0.180 |
rs2274062 | 13 | 13q22.2 | LMO7 | A/T | 0.453 | 0.498 | 0.15 | 0.84 (0.66–1.06) | 0.145 |
rs9318375 | 13 | 13q22.2 | LMO7 | T/A | 0.043 | 0.058 | 0.24 | 0.72 (0.41–1.27) | 0.254 |
rs2732044 | 15 | 15q11.2 | SNORD109B | A/G | 0.427 | 0.442 | 0.90 | 0.94 (0.74–1.20) | 0.623 |
rs1030389 | 15 | 15q11.2 | SNORD109B | G/A | 0.439 | 0.467 | 0.34 | 0.90 (0.70–1.14) | 0.371 |
rs1045935 | 15 | 15q11.2 | SNORD109B | G/T | 0.540 | 0.486 | 0.72 | 1.24 (0.98–1.58) | 0.076 |
rs12902710 | 15 | 15q21.3 | PIGB | C/T | 0.500 | 0.461 | 0.34 | 1.17 (0.92–1.49) | 0.209 |
rs9931702 | 16 | 16q12.2 | AKTIP | T/C | 0.271 | 0.339 | 0.90 | 0.73 (0.56–0.95) | 0.018 |
rs9302648 | 16 | 16q12.2 | AKTIP | T/G | 0.269 | 0.339 | 0.90 | 0.72 (0.55–0.94) | 0.014 |
p- value ≤ 0.05 indicates statistical significance.
HWE, Hardy-Weinberg Equilibrium; MAF, minor allele frequency; ORs, odds ratios; CI, confidence interval.