Table 5. The associations between the gene polymorphisms and clinical characteristics of cervical cancer patients.
SNP | clinical stages | subtype | ||||||
---|---|---|---|---|---|---|---|---|
I- II | III- IV | Squamous carcinomas | adenocarcinoma | |||||
OR (95%CI) | p | OR (95%CI) | p | OR (95%CI) | p | |||
rs1048512 | 0.57 (0.34–0.96) | 0.033 | 1.38 (0.85–2.24) | 0.194 | 0.88 (0.59–1.31) | 0.536 | 0.53 (0.07–4.06) | 0.532 |
rs6659346 | 0.60 (0.36–0.99) | 0.044 | 1.54 (0.97–2.45) | 0.066 | 0.96 (0.65–1.4) | 0.818 | 0.5 (0.07–3.85) | 0.498 |
rs11006369 | 1.47 (0.95–2.28) | 0.085 | 1.2 (0.7–2.07) | 0.502 | 1.32 (0.89–1.96) | 0.167 | 2.25 (0.62–8.15) | 0.205 |
rs2862833 | 1.01 (0.77–1.34) | 0.920 | 1.45 (1.04–2.03) | 0.028 | 1.12 (0.87–1.42) | 0.381 | 2.62 (0.9–7.65) | 0.067 |
rs3741216 | 0.71 (0.39–1.29) | 0.263 | 1.55 (0.89–2.72) | 0.122 | 1.02 (0.64–1.63) | 0.920 | 1.8 (0.39–8.17) | 0.442 |
rs217727 | 1.81 (1.33–2.46) | 0.000 | 1.23 (0.84–1.8) | 0.289 | 1.55 (1.18–2.04) | 0.002 | 1.11 (0.35–3.51) | 0.856 |
rs2839702 | 0.86 (0.64–1.15) | 0.308 | 0.86 (0.61–1.22) | 0.409 | 0.88 (0.69–1.14) | 0.331 | 0.96 (0.34–2.68) | 0.940 |
rs2067051 | 0.76 (0.56–1.03) | 0.073 | 0.92 (0.65–1.3) | 0.623 | 0.84 (0.65–1.08) | 0.170 | 1 (0.36–2.78) | 0.994 |
rs2274062 | 0.77 (0.58–1.02) | 0.067 | 0.99 (0.71–1.38) | 0.930 | 0.83 (0.65–1.06) | 0.134 | 1.01 (0.37–2.72) | 0.989 |
rs9318375 | 0.98 (0.54–1.80) | 0.959 | 0.37 (0.13–1.05) | 0.051 | 0.71 (0.4–1.26) | 0.237 | 1.08 (0.14–8.47) | 0.938 |
rs2732044 | 1.10 (0.83–1.46) | 0.494 | 0.7 (0.5–0.99) | 0.043 | 0.93 (0.73–1.19) | 0.571 | 1.26 (0.47–3.41) | 0.646 |
rs1030389 | 1.04 (0.79–1.38) | 0.783 | 0.68 (0.48–0.96) | 0.028 | 0.89 (0.7–1.13) | 0.341 | 1.14 (0.42–3.09) | 0.792 |
rs1045935 | 1.07 (0.81–1.42) | 0.627 | 0.6 (0.43–0.85) | 0.004 | 0.79 (0.62–1) | 0.053 | 0.63 (0.23–1.77) | 0.381 |
rs12902710 | 1.25 (0.94–1.65) | 0.121 | 1.02 (0.73–1.43) | 0.895 | 1.15 (0.9–1.46) | 0.267 | 1.95 (0.7–5.42) | 0.196 |
rs9931702 | 0.68 (0.50–0.93) | 0.015 | 0.87 (0.61–1.24) | 0.441 | 0.75 (0.57–0.97) | 0.029 | 0.28 (0.06–1.24) | 0.074 |
rs9302648 | 0.68 (0.50–0.93) | 0.015 | 0.85 (0.59–1.21) | 0.363 | 0.74 (0.57–0.96) | 0.024 | 0.28 (0.06–1.24) | 0.074 |
CI, confidence interval; ORs, odds ratios; p-value ≤ 0.05 indicates statistical significance.