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. 2016 Oct 1;7(47):76667–76683. doi: 10.18632/oncotarget.12395

Figure 6. MAVS expression is downregulated in poly(I:C)-treated glial cells.

Figure 6

(A and B) Human U251 cells were transfected with 100ng/ml poly(I:C) for different periods, and MAVS mRNA (A) and protein (B) level was determined with quantitative real-time PCR and immunoblotting, respectively. (C and D) U251 cells were transfected with poly(I:C) with different concentrations for 6h, and and MAVS mRNA (C) and protein (D) level was determined with quantitative real-time PCR and immunoblotting, respectively. Data represent means ± SD from three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001. Protein levels were quantified with immunoblot scanning and normalized to the amount of GAPDH expression.