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. 2016 Oct 13;7(47):77237–77243. doi: 10.18632/oncotarget.12628

Table 2. Prognostic factors analysis based on Cox's proportional hazards model.

Clinical parameters Uni-variate Multi-variate
Hazard ratio 95% CI P-value Hazard ratio 95% CI P-value
Gender
 Male / Female 0.780 0.473-1.286 0.329 0.898 0.553-1.515 0.688
Age (years)
 ≥ 60 / < 60 1.100 0.688-1.759 0.690 1.038 0.638-1.689 0.880
Tumor size (cm)
 ≥ 3.5 / < 3.5 2.213 1.319-3.711 0.003 2.101 1.228-3.596 0.007
TNM Stage
 SIII+IV / SI+II 1.886 1.168-3.044 0.009 1.758 1.079-2.864 0.024
B7-H3 and -H4 combined
 Both high / others 2.066 1.272-3.355 0.003 1.876 1.155-3.046 0.011

Values in bold signify P < 0.05.