Figure 3.

NO inhalation reduces basilar arterial spasm. (a) SAH was induced by injecting blood into the cisterna magna; saline was injected as a sham treatment. Representative photomicrographs of a saline-injected brain (left), an SAH-induced brain (middle), and the brain of an animal that received iNO treatment for 12 h following SAH induction (right). (b) Quantification of the diameter of the basilar artery in saline-injected (Sham) mice and SAH-induced mice after 1 and 12 h with or without iNO treatment. The positive effect of iNO observed 12 h after SAH is abated at 24 and 48 h (data not shown).