Figure 5.

iNO treatment improves outcome following experimental SAH. (a). After SAH (day 0), control animals developed severe neurological deficits measured using a multivariate neurological score (higher scores indicate poorer performance). This impaired neurological performance remained significant through the observation period. In contrast, neurological outcome was significantly better in iNO-treated animals from the third day after SAH, with the iNO-treated mice reaching baseline performance by day 6. (b) Survival plots of mice that were subjected to SAH, then iNO-treated or control-treated for 23 h. The 72-h survival rate in the control-treated mice was 70%, whereas the survival rate in the iNO-treated mice was 100%.