Figure 1.

Exclusion/inclusion criteria and frequency of brain arteriolosclerosis (B-ASC) pathology in autopsied cases from the National Alzheimer's Coordinating Center (NACC) data set. (a) Living cases and autopsied cases with missing information which would preclude making an assessment of B-ASC status were excluded from analysis. (b) The percentage of cases with any B-ASC pathology (mild, moderate or severe) in the NACC data set. Asterisk (*) indicates that 64 cases with age at death <50 years or > 100 years were not plotted. (c) A stacked bar graph showing that B-ASC severity increases with age at death, Chi-square p-value < 0.0001.